28 Jul 2026
Signal Headquarters
Vol. I
No. 159
Reference

What is creatine?

Creatine is a compound that can be taken as a supplement, with effects on muscle and brain function.

  • Mar 2026 - Dr. Rhonda Patrick reported that many creatine gummies sold commercially were found to contain no actual creatine when tested.
  • Jun 2026 - Darren Candow stated that a study of 20 Alzheimer’s patients taking 20 grams daily for 8 weeks increased brain creatine by 11% and improved cognitive test scores.
  • Jun 2026 - Darren Candow noted that young athletes taking 5 grams daily slept an average of 1 hour longer on training days.
  • Jun 2026 - Darren Candow said that in skeletal muscle, elevated creatine levels take about a month to return to baseline, while in the brain it may take 5 weeks to 3 months.
  • Jun 2026 - Dr. Stephanie Estima said that a 10-gram dose of creatine can help with cognition, awareness, and alertness on nights with no sleep, as it is harder to cross the blood-brain barrier.
Signal Headquarters · reference note, compiled from attributed expert discussion.